Josh’s Journey to the Stem Cell Institute in Panama for Spinal Cord Injury Treatment

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Monday, October 5, 2015

Josh Rivers Weights“Ok these stem cells might really be kicking in now! One of the leg machines I use I have only been able to do 30lbs max, over the last few months of going to the gym 3 times a week. Today all of a sudden I am able to do 70!!!!??? I am really in shock right now to see an increase like this out of nowhere.. just 2 days ago I was struggling with 30!! I was also able to add more weight to 2 out of the other 4 leg machines I use. I can’t believe it!!”

Note: The stem cell treatment protocol Josh underwent included multiple intravenous and intrathecal (into the spinal fluid) injections of umbilical cord tissue-derived mesenchymal stem cells and his own bone marrow-derived mesenchymal stem cells administered over the course of one month. For more information about stem cell therapy for spinal cord injury, visit:

Biologic augmentation of rotator cuff repair with mesenchymal stem cells during arthroscopy improves healing and prevents further tears: a case-controlled study.

Int Orthop. 2014 Sep;38(9):1811-8. doi: 10.1007/s00264-014-2391-1. Epub 2014 Jun 7.

Hernigou P, Flouzat Lachaniette CH, Delambre J, Zilber S, Duffiet P, Chevallier N, Rouard H.


Rotator Cuff

Rotator Cuff

PURPOSE:  The purpose of this study was to evaluate the efficiency of biologic augmentation of rotator cuff repair with iliac crest bone marrow-derived mesenchymal stem cells (MSCs). The prevalence of healing and prevention of re-tears were correlated with the number of MSCs received at the tendon-to-bone interface.

METHODS:  Forty-five patients in the study group received concentrated bone marrow-derived MSCs as an adjunct to single-row rotator cuff repair at the time of arthroscopy. The average number of MSCs returned to the patient was 51,000 ± 25,000. Outcomes of patients receiving MSCs during their repair were compared to those of a matched control group of 45 patients who did not receive MSCs. All patients underwent imaging studies of the shoulder with iterative ultrasound performed every month from the first postoperative month to the 24th month. The rotator cuff healing or re-tear was confirmed with MRI postoperatively at three and six months, one and two years and at the most recent follow up MRI (minimum ten-year follow-up).

RESULTS:  Bone marrow-derived MSC injection as an adjunctive therapy during rotator cuff repair enhanced the healing rate and improved the quality of the repaired surface as determined by ultrasound and MRI. Forty-five (100 %) of the 45 repairs with MSC augmentation had healed by six months, versus 30 (67 %) of the 45 repairs without MSC treatment by six months. Bone marrow concentrate (BMC) injection also prevented further ruptures during the next ten years. At the most recent follow-up of ten years, intact rotator cuffs were found in 39 (87 %) of the 45 patients in the MSC-treated group, but just 20 (44 %) of the 45 patients in the control group. The number of transplanted MSCs was determined to be the most relevant to the outcome in the study group, since patients with a loss of tendon integrity at any time up to the ten-year follow-up milestone received fewer MSCs as compared with those who had maintained a successful repair during the same interval.

CONCLUSION:  This study showed that significant improvement in healing outcomes could be achieved by the use of BMC containing MSC as an adjunct therapy in standard of care rotator cuff repair. Furthermore, our study showed a substantial improvement in the level of tendon integrity present at the ten-year milestone between the MSC-treated group and the control patients. These results support the use of bone marrow-derived MSC augmentation in rotator cuff repair, especially due to the enhanced rate of healing and the reduced number of re-tears observed over time in the MSC-treated patients.

Stem Cell Treatments for Autism – “Oh my god the speech!!! He’s TALKING I mean real speech and conversation!!! Today was crazy!!!”

This new facebook update on Anthony Guerriero says it all:

Autism Stem Cell Patient Anthony Guerriero

“Oh my god the speech!!! He’s TALKING I mean real speech and conversation!!! Today was crazy!!! Anthony was TELLING us all about his birthday, what he wants to do, counting down the days, what presents he wants, what he wants from Santa vs his birthday, all about Halloween and what each of us is going to be (Mommy is Blue toad, Bella is princess peach, daddy is luigi and Anthony now wants to be Mario), telling us what all the costumes are and what he’s wearing, what he did in school today, what he’s doing tomorrow for his last day, what he wants to play with and with who, what he wants for dinner (tried a new food too), how many days til we go to Maine, what we’re going to do there!!!!!! And on and on. Crazy crazy crazy!!! All spontaneous!!! All TALKING !!! It’s happening big time!!!!! WOW!!!”

Anthony Guerriero FB Comments 8-4-15

Anthony Guerriero FB Comments 8-4-15

Visit Anthony’s Facebook Page Here

Read original news story about Anthony here: Autistic Woodbridge boy making strides after stem cell treatment in Panama

Stem Cells Targeting Inflammation as Potential Anti-aging Strategies and Therapies

Rafael Gonzalez, Dave Woynarowski and Luis Geffner

The use of stem cells as anti-aging therapies may offer many an alternative method of slowing down or deterring several of the detrimental aspects of aging


Human aging is associated with a vast array of clinical disorders that all relate to the body’s inability to maintain homeostasis. In our bodies, the healing process requires tight control of the acute inflammatory response. When the levels of inflammatory markers such as interleukin-6, tumor necrosis factor alpha, and C-reactive protein are elevated, there is a direct correlation with several chronic diseases of aging such as cardiovascular disease, cognitive decline, and physical disability. Extensive studies have shown strong evidence that elevated levels of these pro-inflammatory mediators may predict disease and disability in the aging population. As there is no cure for aging, a key question is how to modulate the effects of inflammation on aging and how to maintain healthy aging. Stem cells offer alternative approaches for treating various diseases/disorders. The use of stem cells as immune system modulators has shown tremendous promise. Mesenchymal stem cells (MSCs) have specific immunomodulatory properties that may help control inflammation. Several animal studies demonstrate that intravenous infusions of MSCs can decrease the pro-inflammatory response while increasing the anti-inflammatory response. Moreover, human clinical studies using MSCs in autoimmune and other inflammatory diseases have demonstrated modulation of the inflammatory response. Therefore, the use of stem cells as anti-aging therapies may offer many an alternative method of slowing down or deterring several of the detrimental aspects of aging.

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Update on Glenburn Boy Who Underwent Stem Cell Therapy for Autism in Panama


JUN 8, 20155:54 PM EDT

In 2009, an 8-year old Glenburn boy became the first child in Maine, and one of less than a hundred nationwide, to undergo stem cell therapy to treat his autism.

TV5 has followed the journey of Kenneth Kelley as he travelled to Panama for treatments.

It’s been about two years since his last transfusion.

Joy Hollowell checked in with the now 14-year old to see how he’s doing.
Like most brothers, 16-year old Philip and 14-year old Kenneth Kelley enjoy challenging each other on video games.

“Who is better?

Kenneth points to Philip

Typical teenager is how most would describe Kenneth…something his parents couldn’t be happier to hear.

Kenneth was diagnosed with autism when he was two.

“Many reputable people told us that he should be put in an institution,” explains Donald Kelley, Kenneth’s father. “And that just made us more determined to find a cure for him. We knew there was one out there somewhere, there had to be.”

Like many parents of autistic kids, Donald and Marty Kelley went to numerous doctors and tried countless treatments, including installing a hyperbaric chamber inside their home.

They had read about stem cell therapy. but the clinic was in Panama, and it was still a relatively new therapy.

“Seeing doctors who tell you things that finally after a while you meeting everybody and you say to yourself, well yeah, OK, yeah, I’ve heard this before,” says Donald Kelley, expressing his frustration.

The Kelleys would spend the next two years researching stem cell therapy for autism, including visiting the clinic in Costa Rica.

“This was different,” says Donald Kelley, “this was totally different.”

Kenneth underwent his first cord blood infusion at the age of 8. That very next morning, The Kelleys say they saw a difference. Within a year, Kenneth was reading and communicating. He went back five more times, until the age of 12.

“The improvements that we saw with Kenneth were amazing,” says his father. “To see your child become you know, enjoying life.”

“Before stem cells, he was just off the charts most of the time,” says Kenneth’s brother, Philip. “Screaming, kicking. I don’t remember him ever actually having a conversation with me. He’s gone from more of a person that I had to take care of to a friend.”

8-year old Caroline calls her big brother a dolphin.

“because he’s very playful and he’s very nice and intelligent,” she explains.

“It was a true blessing that he got as far as he did,” says Donald Kelley. “And that he’s where he is today.”
The Kelleys say for now, Kenneth is done with treatments. However, they would consider going back, depending upon their son’s progression.

They tell other parents of autistic kids to never give up.

Duchenne’s Patient Ryan Benton Discusses His Experience with Stem Cell Therapy

Ryan Benton is the first patient in the United States to receive human umbilical cord-derived mesenchymal stem cell therapy for Duchenne’s muscular dystrophy. The US FDA granted Ryan this trial under compassionate use. Ryan first began treatments at the Stem Cell Institute in Panama before being able to receive treatments in his hometown of Wichita, Kansas.

Copa Airlines Magazine Features Stem Cell Therapy at the Stem Cell Institute in Panama

Clinical Trials for Multiple Sclerosis and Rheumatoid Arthritis using Umbilical Cord Tissue Mesenchymal Stem Cells

Stem Cell Institute and Medistem Panama founder, Neil Riordan, PhD discusses clinical trials for multiple sclerosis and rheumatoid arthritis using umbilical cord tissue-derived mesenchymal stem cells at our fall stem cell seminar in San Antonio.

For more information about these trials and others, please visit The multiple sclerosis trial is full but the RA trial is still recruiting as of November 24, 2014.

Highlights include:

How do we select umbilical cords for use? Medistem has identified proteins and genes in the cells that allow us to screen hundreds of umbilical cords to select only the ones containing the specific types of cells that have the best anti-inflammatory properties, the best immune modulating capacity and the best ability to stimulate regeneration.

How therapy using umbilical cord tissue-derived mesenchymal stem cells (MSCs) differs from bone marrow transplants used in cancer patients.

Properties of umbilical cord MSCs:

  • Modulate the immune system
  • Increase the number of T-regulatory cells
  • Block clonal expansion of activated T cells
  • MSCs in patients with autoimmune diseases don’t work properly

How demyelination occurs in MS patients and how MSCs act on the immune system to slow it down or stop it.

Treated MS patient follow-up survey results at 120 days and 1 year after treatment.

Television news story about Sam Harrell’s return to coaching football after severe MS symptoms forced him into early retirement.

Results from a 172 patient study on treating rheumatoid arthritis with intravenous umbilical cord tissue mesenchymal stem cells in which all patients improved.

Trial Information

These trials may be viewed on the National Institutes of Health web site

Umbilical Cord Tissue-derived Mesenchymal Stem Cells for Rheumatoid Arthritis

Feasibility Study of Human Umbilical Cord Tissue-Derived Mesenchymal Stem Cells in Patients With Multiple Sclerosis

Those interested in stem cell therapy for MS may still apply for private treatment on this site.

A Review of Therapeutic Effects of Mesenchymal Stem Cell Secretions and Induction of Secretory Modification by Different Culture Methods

Another competitive ballroom dancer back in the game after stem cell therapy

Emerald IEditor’s Note: Deborah received human umbilical cord tissue-derived mesenchymal stem cells

My name is Deborah, from Southern California.

Occupation: Certified Interior Designer with a Masters degree in Interior Design.

Diagnosis: Patella chondromalacia with thinning of cartilage, mostly involving the medial facet and at the median. There is early degenerative changes with small marginal spurs involving the femoral patellar compartment and the medial and lateral femorotibial compartments. There is no fracture, osteochondral or loose body. Also localized inflammation of the Hoffa’s fat pad, anterior to the transverse. (All of these findings were from an MRI taken on June 15, 2011).

Symptoms before treatment: severe pain, difficulty in walking, bending, standing, sitting, exercising, sleeping…life was not fun.

Treatments/drugs: Aleve, Tylenol, Celebrex, acupuncture, physical therapy, custom brace, ace elastic braces, interviewed /consults with three independent orthopedic surgeons, possible knee replacement, arthroscopic surgery to mend torn meniscus.

My friend and ballroom dance competitor, Dr. Janet Vaughan convinced me after I had been researching other alternatives here in the United States for over a year, to contact Dr. Barnett at the Stem Cell Institute in Panama City, Panama to see if I was a candidate for stem cell therapy. Janet was kind enough to email Dr. Barnett for me and tell her I would be filling out the paperwork online and sending it to her ASAP. Dr. Barnett was extremely responsive and my husband and I soon had a conference call with Dr. Paz Rodriguez. He was kind, gracious and patient with all of our questions. We were soon on our way with an appointment to have stem cell therapy in Panama City, Panama!

I am now able to get back to my competitive ballroom dancing and doing well! I have less pain going up and down stairs (even though I am careful and always aware of my knees), I walk easier, exercise and am back to a normal life style. Am I at 100% ? No…but at 62 years old and being athletic all my life with snow skiing, water skiing, volleyball, tennis, racquetball, zoomba and other athletic movements I feel terrific even if I am at 80-90% of my capability! We are back to travelling the world and I am thrilled… I am living my life! And my knee is not dictating my life.

Impression of the clinic: The doctors, staff and driver, Javier were fabulous!!! Everyone made me and my husband feel comfortable and all were compassionate, personable, professional, helpful, friendly and always welcome to keep in touch! They always welcomed all of our questions and never made us feel uncomfortable in asking! Dr. Hernandez was with me all the way and gave me his cell number 24/7 and helped me through the language barrier since my Spanish is quiet weak! Everyone was just great!!!

What would I tell someone considering stem cell therapy: Do your homework… research and get referrals! You have nothing to lose and a life to gain! The Stem Cell Institute is terrific in their work and research! I have told many of my friends and individuals who find out through others that I had stem cell therapy. Unfortunately none have moved forward and try other options and still have no results…I feel sorry for them! Some do…and some do not.