Liposuction method can adversely affect adipose tissue-derived stem cell yield and growth

Adipose tissue-derived mesenchymal stem cell yield and growth characteristics are affected by the tissue-harvesting procedure which was published in Cytotherapy (vol. 8 issue 2, 2006, pages 166-177)states that: "Ultrasound-assisted liposuction resulted in a lower frequency of proliferating adult stem cells, as well as a longer population doubling time of adult stem cells, compared with resection..." [...]

2013-01-24T21:20:55+00:00January 24th, 2013|Adipose Stem Cells, liposuction, News, Stem Cell Research|

Patients beware: “Point of care” fat stem cell separation and counting kits inaccurate and not US FDA approved for humans.

An informative paper by Mary Pat Moyer, PhD detailing why "same-day" fat stem cell kits that are becoming more common in doctors' offices across the US can miscount "stem cells" by large factors leading to over estimation of stem cell counts by as much as 20 times or more. It also states, "no complete harvest [...]

2013-01-22T23:15:25+00:00January 22nd, 2013|Adipose Stem Cells, Adult Stem Cells, News, Stem Cell Research|

Could Metabolic Syndrome, Lipodystrophy, and Aging Be Mesenchymal Stem Cell Exhaustion Syndromes?

Eduardo Mansilla,1,* Vanina Díaz Aquino,1 Daniel Zambón,2 Gustavo Horacio Marin,1 Karina Mártire,1 Gustavo Roque,1 Thomas Ichim,3 Neil H. Riordan,3 Amit Patel,4 Flavio Sturla,5 Gustavo Larsen,6, 7 Rubén Spretz,6, 7 Luis Núñez,8, 9 Carlos Soratti,10 Ricardo Ibar,10 Michiel van Leeuwen,11 José María Tau,1 Hugo Drago,5 and Alberto Maceira1 Abstract One of the most important and complex [...]

2012-09-26T17:21:57+00:00September 26th, 2012|News, Stem Cell Research|

Why does fat (adipose) stem cell therapy take more than one week?

Intravenously administered adipose-derived stem cells will tend to migrate back to the fresh wound site if it is not given an adequate time to heal. Therefore, it is essential to allow about one week after the mini-liposuction before administering any stem cells intravenously. Otherwise, there is a likelihood that the treatment will not be as [...]

Multiple Sclerosis Treatment Success Using Mesenchymal Stem Cell-Secreted Factors in Animal Model

Stem cell researchers at Case Western Reserve have reported in Nature Magazine that the functional deficits caused by multiple sclerosis can be reduced by administering mesenchymal stem cell secreted factors. While previous studies have shown promising results using mesenchymal stem cells, this is the first time that such results have been reported without using the [...]

First patient to get stem cell therapy identified

By Rob Stein, The Washington Post Embryonic stem cells have numerous pitfalls in addition to the ethical dilemmas. While the concept of a “blank slate” cell is extremely attractive in terms of generating new tissues for transplantation and organ replacement, the problem is that these cells are so young that they do not properly “know” [...]

2012-04-07T19:51:08+00:00April 7th, 2012|Clinical Trials, News, Stem Cell Research|

Making Blood Cells into Heart Cells

Vojdani et al. Hum Cell. 2011 Mar;24(1):35-42 One of the major debates in the area of stem cell therapy is whether adult stem cells are capable of directly transforming (differentiating) into new tissue, or whether the therapeutic effects of administered stem cells occur because of growth factors produced by the injected stem cells. There are [...]

2012-03-31T19:56:18+00:00March 31st, 2012|Heart Disease, News, Stem Cell Research|

Stemedica Treats First Patient with Ischemic Allogeneic Mesenchymal Stem Cells

Stemedica Cell Technologies Press Release The San Diego stem cell company Stemedica Cell Technologies, Inc reported treatment of its first patient as part of a 35 patient clinical trial in stroke patients. The study uses bone marrow stem cells that have been preconditioned with hypoxia and used in a non-matched manner. The trial is being [...]

Stem Cells in Theory and Practice

Dr. Douglas J. Herthel of Alamo Pintado Equine Medical Center in Los Olivos, California was one of the first practitioners to use stem cells, beginning in 1995. Herthel used stem cells from bone marrow to treat ligament and tendon injuries in horses. The results from these treatments were so promising that he began using stem [...]

2012-02-15T20:26:29+00:00February 15th, 2012|News, Stem Cell Research|