Medistem and Licensee ERCell Receive Russian Regulatory Approval for the RECOVER-ERC Trial

The clinical trial, Non-Revascularizable IschEmic Cardiomyopathy treated with Retrograde COronary Sinus Venous DElivery of Cell TheRapy (RECOVER-ERC), is being led by Principle Investigator Dr. Leo Bockeria, Chairman of the Backulev Center http://www.bakulev.ru/en/about/director/. The Backulev Center is Russia's premier institute for cardiovascular surgery and cardiology. Every year the Backulev Center performs approximately 30,000 diagnostic and treatment [...]

2012-01-24T18:45:51+00:00January 24th, 2012|Adult Stem Cells, Heart Disease, News, Stem Cell Research|

PRECISE: Adipose-derived stem cells show utility as therapy

Cardiology Today PRECISE is The Randomized Clinical Trial of Adipose-Derived Stem Cells in Treatment of Non Revascularizable Ischemic Myocardium, a double blind, placebo-controlled trial involving 27 patients with chronic ischemic heart disease with HF, angina or both, who were not eligible for percutaneous or surgical revascularization. The patients in the study underwent a liposuction to [...]

Scientists look to stem cells to mend broken hearts

Cardiac medicine has traditionally been associated with innovative procedures that sometimes where considered heretical to the present day dogma. For example, the first heart transplant, the use of the balloon catheter, the introduction of thrombolytics, all met substantial resistance from the “establishment” in their time. It appears that the next revolution in cardiac medicine is [...]

2011-02-01T21:02:22+00:00February 1st, 2011|Adult Stem Cells, Bone Marrow, Heart Disease, News, Stem Cell Research|

Stem Cell Institute in Panama Collaborates on New Method of Treating Diabetes-Associated Heart Disease

Zhang et al. Journal of Translational Medicine Diabetes is associated with numerous “secondary complications” including premature heart disease, renal failure, critical limb ischemia (an advanced form of peripheral artery disease) and diabetic retinopathy. One of the common features of these secondary complications is that they are all associated with low levels of circulating endothelial progenitor [...]

2010-12-15T15:22:40+00:00December 15th, 2010|Diabetes, Heart Disease, News, Stem Cell Research|

Stem cell therapy benefits patients with chronic heart failure—study

(Neharika Sabharwal) After a heart attack the myocardium (heart muscle) undergoes a period of damage during which cells of the body attempt to heal the injured tissue. This occurs through stem cells found in the heart itself, called cardiac specific stem cells (CSC) as well as bone marrow stem cells which seem to exit the [...]

2010-08-31T15:52:21+00:00August 31st, 2010|Adult Stem Cells, Heart Disease, News, Stem Cell Research|

Stem Cell Institute Panama Clinic Case Report of Successful Treatment of Heart Failure Patient Published

Adult stem cell therapy is currently in numerous clinical trials in the United States and Internationally. A sample of ongoing trials can be seen at www.clinicaltrials.gov if you search for the words "stem cell". In clinical trials the objective is to determine safety (in Phase I), efficacy in an unblinded manner (Phase II) and efficacy [...]

Stem Cells Don’t have to be Alive to Be Beneficial

The use of stem cells in patients who have poor circulation is well-known.  In fact, the first use of stem cells for conditions other than blood disorders was in patients who were undergoing bypass surgery.  Usually patients undergo bypass because of advanced atherosclerosis that is inhibiting the flow of blood to the heart muscle.  Despite [...]

2010-04-30T17:55:51+00:00April 30th, 2010|Heart Disease, News, Stem Cell Research|

Magnetic Attraction of Stem Cells to Injured Heart Creates Potent Treatment

The intracoronary administration of bone marrow stem cells in patients who have suffered a heart attack has been demonstrated to cause beneficial effects in double blind studies, as discussed in this video http://www.youtube.com/watch?v=flv0RmzPyLU. Intracoronary administration has potential side effects since a balloon needs to be expanded in the area where the heart attack occurred, which [...]

2010-04-12T18:33:16+00:00April 12th, 2010|Adult Stem Cells, Heart Disease, News, Stem Cell Research|

Stem Cell Treatment for Heart Attacks: Timing is Everything

Skeletal myoblasts are a type of muscle-specific stem cell that have been used previously in several clinical trials, particularly for heart failure and post-heart attack patients.  Advantages of this type of stem cell include the fact that they are from adult sources (no risk of cancer), they are already committed to becoming muscle cells, and [...]

2010-03-05T18:55:22+00:00March 5th, 2010|Adult Stem Cells, Heart Disease, News, Stem Cell Research|