Immune Cells Killing Stem Cells and Stem Cells Killing Immune Cells

Knight et al. J Neurol Sci. Several studies have demonstrated that stem cells are useful in the treatment of multiple sclerosis. The Cellmedicine clinic published previously in collaboration with the University of California San Diego that 3 patients treated with their own fat derived stem cells entered remission. Other studies are ongoing, including a study [...]

Limb Transplants Facilitated by Bone Marrow Stem Cells

Kuo et al. Plast Reconstr Surg. 2011 Feb;127(2):569-79. Composite tissue allografts are usually transplants of anatomical structures that contain multiple types of tissues. We have seen numerous high-profile examples of human composite tissue allografts such as whole hands, faces, and arms. While advancement of surgical techniques have made such transplants a reality, immunologically-mediated rejection remains [...]

2011-02-01T20:59:47+00:00February 1st, 2011|Adult Stem Cells, Bone Marrow, News, Stem Cell Research|

How Inflammation Suppresses Stem Cell Function

Wang et al. PLoS One;5(12):e14206. Low grade inflammation is well known to correlate with development of numerous disease conditions such as heart failure, kidney failure, and diabetes. It is generally accepted that oxidative stress caused by inflammation is one of the means by which disease evolution occurs. Inflammatory conditions usually generate oxygen free radicals that [...]

2010-12-03T15:25:59+00:00December 3rd, 2010|Adult Stem Cells, News, Stem Cell Research|

Why should mesenchymal stem cells (MSCs) cure autoimmune diseases?

Uccelli A, Prockop DJ. Curr Opin Immunol. 2010 Dec;22(6):768-74. Epub As many readers of Cellmedicine News most likely realize, the concept of stem cell therapy is still relatively controversial. Despite the fact that clinical trials have demonstrated therapeutic signals that various stem cells are useful in treatment of diseases ranging from multiple sclerosis, to type [...]

2010-11-17T15:38:04+00:00November 17th, 2010|Autoimmune Disease, News, Stem Cell Research|

What Works Better: Stem Cell Mobilization or Stem Cell Administration for Brain Injury

Bakhtiary et al. Iran Biomed J. 2010 Oct;14(4):142-9. Bone marrow mobilization is used as part of hematopoietic stem cell transplantation in order to collect donor bone marrow stem cells without having to puncture the bone. The process of mobilization is induced by administration of the drug G-CSF, which is approved by the FDA. One interesting [...]

2010-10-14T15:43:48+00:00October 14th, 2010|Adult Stem Cells, Brain Injury, News, Stem Cell Research|

Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study.

Liang et al. Ann Rheum Dis. 2010 Aug;69(8):1423-9. Mesenchymal stem cells are unique in that on the one hand they are capable of differentiating into a variety of tissues, but on the other hand they also are potently anti-inflammatory and immune modulatory. Evidence of immune modulation comes from studies that show mesenchymal stem cells: a) [...]

2010-08-02T16:44:47+00:00August 2nd, 2010|Adult Stem Cells, Lupus, News, Stem Cell Research|

Stem Cells for Spinal Cord Injury

The use of mesenchymal stem cells for a variety have diseases has been published. This includes conditions such as heart failure, liver failure, stroke, and lupus. One of the attractive features of mesenchymal stem cells is that they can differentiate into numerous tissues while at the same time exerting anti-inflammatory activities. In the situation of [...]