Therapeutic Effects of Intra-Arterial Delivery of Bone Marrow Stromal Cells in Traumatic Brain Injury of Rats—In Vivo Cell Tracking Study by Near-Infrared Fluorescence Imaging

Neurosurgery: February 2012 – Volume 70 – Issue 2 – p 435–444 doi: 10.1227/NEU.0b013e318230a795 Research-Animal Osanai, Toshiya MD, PhD*; Kuroda, Satoshi MD, PhD*; Sugiyama, Taku MD, PhD*; Kawabori, Masahito MD*; Ito, Masaki MD*; Shichinohe, Hideo MD, PhD*; Kuge, Yuji PhD‡; Houkin, Kiyohiro MD, PhD*; Tamaki, Nagara MD, PhD‡; Iwasaki, Yoshinobu MD, PhD* Abstract BACKGROUND: A…

What Works Better: Stem Cell Mobilization or Stem Cell Administration for Brain Injury

Bakhtiary et al. Iran Biomed J. 2010 Oct;14(4):142-9. Bone marrow mobilization is used as part of hematopoietic stem cell transplantation in order to collect donor bone marrow stem cells without having to puncture the bone. The process of mobilization is induced by administration of the drug G-CSF, which is approved by the FDA. One interesting…

Hope for Brain Injury Victims

Traumatic brain injury (TBI) is a major health problem caused by a sudden trauma to one or more areas of the brain. Today the conventional method of treating patients with TBI is based on administration of supplements to rebalance the brain’s chemistry. In the early phases of TBI reduction of the ongoing inflammation using various…