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Research
Bioinformatics Company Launches Stem Cell Collaboration
Reuters
September 1, 2009
One of the leading bioinformatics companies, GeneGo, announces the new MetaMiner Stem Cell Project in collaboration with scientists from industry and academia.
Cells Reprogrammed With Single Gene
Nature
August 28, 2009
Scientists in Germany have simplified the iPS (induced pluripotent stem) cell reprogramming procedure from four genes to one gene, though the choice of cell type plays an important role.
Stem Cell Breakthrough for Huntington's Disease
University of Rochester Medical Center
September 26, 2007
Paying close attention to how a canary learns a new song has helped scientists open a new avenue of research against Huntington's disease -- a fatal disorder for which there is currently no cure or even a treatment to slow the disease.
Stem Cells from Testicles - Another Non-Controversial Breakthrough
ABC News
September 20, 2007
United States researchers have come up with a novel use for men's testicles, which they say are a rich source of stem cells and so could be transformed into a wide range of tissue types to help fight disease. The scientists say they have managed to isolate stem cells from the testes of male mice, extract them and reprogram them into blood vessels, heart cells and tissue.
Adult Stem Cell Research Continues Encouraging Path
The Review / Osprey News Network
August 20, 2007
Better understanding of stem cells could lead to a better understanding of birth defects and diseases like cancer. But while medical researchers, and indeed some patients, are excited at the prospects, the catch is the ethical question: Is it morally proper to initiate reproduction, only to harvest the days-old embryo for its stem cells? Or are adult stem cells truly the better and more proven option?
Respected Japanese Researcher Brings More Stem Cell Science to California
Mercury News
August 17, 2007
A Japanese pioneer in stem-cell research is opening a lab in San Francisco, a significant milestone in the state's bid to become an international draw for the world's leading regenerative medicine experts. Last year, Shinya Yamanaka of Kyoto University was the first to identify genes in mouse skin cells that allow scientists to "reprogram" the cells to an embryonic state from which they could create some tissue types.
Scientists Gain More New Understanding of Adult Stem Cell Regulation
Innovations Report
August 8, 2007
Forsyth Institute scientists have discovered an important mechanism for controlling the behavior of adult stem cells. Research with the flatworm, planaria, found a novel role for the proteins involved in cell-to-cell communication. This work has the potential to help scientists understand the nature of the messages that control stem cell regulation.
Japanese Adult Stem Cell Research May End Embryo Debate
LifeSiteNews.com
July 20, 2007
Since its publication in the journals Nature and Stem Cell on June 7, a report that Japanese researchers have produced embryo-like stem cells from the somatic cells of mice, have made headlines around the world and prompted speculation that the scientific community's brief obsession with cloning experiments for stem cell research is about to end.
Amyloidosis Patients Treated Successfully with Stem Cells
Boston University
July 3, 2007
Researchers from the Stem Cell Transplant Program and the Amyloid Treatment and Research Program at Boston University Medical Center (BUMC) have found that tandem cycles of high-dose chemotherapy and blood stem cell transplantation can help treat patients with immunoglobulin-light chain (AL) Amyloidosis who did not respond to initial treatment with this method.
Pope Supports Adult Stem Cell Research
Bloomberg News
June 27, 2007
Pope Benedict XVI reiterated the Roman Catholic Church's support for stem-cell research, on condition the work doesn't involve human embryos. The pontiff held his traditional weekly general audience at the Vatican today and directed his comments at delegates taking part in a conference at Rome's La Sapienza University on research into the treatment of heart disease with so-called adult stem cells, which exist in tiny numbers in developed organs.
Something Fishy About Stem Cell Treatment?
HealthNewsDigest.com
June 21, 2007
The discovery that zebrafish produce natural chemicals that enhance production of blood-forming stem cells may translate rapidly into new treatments to increase the success of bone marrow or cord blood transplants in humans. In their experiments, the researchers were searching for compounds that would increase the production of blood-forming, or hematopoietic, stem cells (HSCs).
Hunger for Political Power Sends Stem Cell Science Spinning
Washington Post Writers Group
June 15, 2007
The arguments over evolution and global warming alone are enough to make anyone believe that we have red and blue science as well as red and blue states. But nothing has been quite as polarizing over the past six years as the controversy over embryonic and adult stem cells. Stem cells have been a defining issue even among politicians who can't define them.
Researchers Find that Sex Matters When it Comes to Stem Cells
Live Science
June 9, 2007
Stem cells taken from the muscles of female mice are better at regenerating tissue than those taken from male mice, a new study finds. This revelation could have a major impact on the development of stem cells as therapies for many diseases and conditions.
Mouse Skin Cells Engineered to be Identical to Embryonic Stem Cells
Associated Press
June 6, 2007
Scientists have long hoped to bypass the embryo procedure, and simply reprogram ordinary body cells to behave like stem cells. In a leap forward for stem cell research, three independent teams of scientists reported Wednesday that they have produced the equivalent of embryonic stem cells in mice using skin cells without the controversial destruction of embryos.
Paralyzed Rats Walk Again After Human Adult Stem Cell Treatment
Medical News Today
June 6, 2007
Rats paralyzed due to loss of blood flow to the spine returned to near normal ambulatory function six weeks after receiving grafts of human spinal stem cells (hSSCs), researchers from the University of California, San Diego (UCSD) School of Medicine report. The researchers believe that the therapy may eventually be proven even more effective in human patients, who would be able to receive physical therapy once treated.
Muscle Building Stem Cells for Regenerative Therapy
Cell Press
May 31, 2007
A new report confirms the existence of some apparently uncommitted stem cells amongst cells responsible for generating the bulging biceps of body builders and the rippling abs of fitness buffs. The findings could lead to new muscle-regenerating therapies--including cell transplantation regimens and stem cell-replenishing drugs--for people with various muscle-wasting diseases, including muscular dystrophies.
Perianal Fistulas Curable with Adult Stem Cell Treatment
MedPage Today
May 22, 2007
Stem cells derived from a patient's own fat can cure a perianal fistula, a Spanish researcher said. In a phase II clinical trial, patients treated with a combination of fibrin glue and stem cells derived from their own adipose tissue saw their fistulas cured 71% of the time, according to Damian García-Olmo, Ph.D., of La Paz Hospital in Madrid.
UK/Israeli Join Efforts to Develop Stem Cell Therapies for Lung Disease
Science|Business
May 16, 2007
UK stem cell specialist NovaThera Ltd announced a collaboration with its Israeli counterpart Gamida Cell Ltd aimed at developing cell therapies for lung repair and regeneration. “This is a very exciting development, and could be a huge step towards a practical approach to the regeneration and repair of lungs severely damaged by incurable diseases such as emphysema and smoking,” said Julia Polak, founder of NovaThera.
Reserve Stem Cells Come to the Rescue
Johns Hopkins University
May 6, 2007
Johns Hopkins researchers have identified a backup supply of stem cells that can repair the most severe damage to the nerves responsible for our sense of smell. These reservists normally lie around and do nothing, but when neighboring cells die, the scientists say, the stem cells jump into action. A report on the discovery will appear online next week in Nature Neuroscience.
Research Reveals How Adult/Progenitor Cells Repair Tissue
Medical News Today
May 3, 2007
New studies in the laboratory of Dr. Darwin J. Prockop, Director of Tulane University's Center for Gene Therapy, are shedding light on the previously mysterious mechanism through which even relatively small amounts of stem/progenitor cells taken from a patient's own bone marrow enhance repair of damaged tissues. Better understanding of the different mechanisms of these stem/progenitor cells suggests multiple strategies for developing new therapies for a broad range of diseases, says Dr. Prockop. It also may help make such treatments more effective and minimize potential dangers.
Bone Marrow Stem Cells "Germinate" into Sperm Cells
Newcastle University
April 14, 2007
Researchers managed to encourage mesenchymal stem cells (MSCs) to differentiate into reproductive cells, known as germ cells. The cells could be used to produce eggs and sperm for patients suffering from infertility since they are a new source of female and male germ cells. The research, published in the latest edition of the journal Reproduction: Gamete Biology built upon previous research by the group that showed that mouse bone marrow could be used to create spermatagonial cells.
Adult Heart Cell Found to have Same Capability as Embryonic Stem Cell
University of Minnesota
January 20, 2007
A new cell type in adult rat heart tissue has been found by researchers at the University of Minnesota. This gives hope for the possibility of treatments such as the growth of new blood vessels for use in bypass surgery or to repair damaged heart muscle after a heart attack. The cells could be expanded in a lab after being harvested and then used in therapy.
Scientists Investigate Adult Stem Cells Potential to Heal Diseased Heart
PharmaLive
January 15, 2007
In order to determine if a subject’s own stem cells can treat a form of severe coronary artery disease, Rush University Medical Center is becoming one of the first medical centers in the country to participate in The Autologous Cellular Therapy CD34-Chronic Myocardial Ischemia (ACT34-CMI) Trial. "What we’re hoping is that these stem cells will be able to stimulate the growth of new blood vessels to bring more blood and oxygen to the heart muscle," said Dr. Gary.
Device Harvests Adult Stem Cells, Kills Cancer Cells
DrugResearcher.com
January 10, 2007
Sidestepping the contentious use of stem cells derived from embryos, researchers at the University of Rochester have unveiled a new device technology that makes it feasible to harvest stem cells from the blood. Two devices, one to kill the cancer cells and another to enrich the stem cells, have been developed by Michael thanks to the findings.
"Bio-Ink" Printer Creates Muscle and Bone Cells from Adult Stem Cells
Discovery News
January 9, 2007
For the first time, using one type of adult stem cell, scientists have discovered a means by which to produce bone and muscle. The field of tissue engineering moves one step closer to functioning the same way that the body does by using the “bio-ink” printer. The technique could make it easier to produce replacement muscle and bone for people suffering from trauma or tissue diseases.
Amniotic Fluid New Source for Multi-Potent Stem Cells
HealthDay News
January 7, 2007
Scientists on Sunday reported the discovery of a new source of human stem cells that have the capability to develop into many different types of cells, including muscle, bone, fat, blood vessel, nerve and liver cells. These stem cells, found in amniotic fluid, could one day lead to a readily available supply of stem cells that don't come with the ethical problems surrounding embryonic stem cells.
Stem Cells and Old Age Memory Loss Explained
Cosmos Online
December 20, 2006
A shortage of neural stem cells in the brain was formerly thought to be the reason that older people exhibited a reduced capacity to learn and remember. However, new research reveals that the reduced ability may be caused by stem cells in brain dividing less frequently instead.
Adult Hair Follicles an Alternative to Embryonic Stem Cells
Medical College of Wisconsin
December 12, 2006
These cells may be useful to treat Parkinson's disease, multiple sclerosis, Hirschsprung's disease, stroke, peripheral neuropathies and ALS. Certain defects of the heart, and bone defects (degeneration, craniofacial birth defects) could also be treated through neural crest stem cell replacement therapy. These conditons affect an estimated 11 million Americans at an annual cost of more than $170 billion.
From Flab to Fab, Fat to Become a Lifesaver
ChannelNewsAsia.com
October 25, 2006
The very fat that many try to rid themselves of contains baby fat cells. Those stem cells can be isolated form the tissue, cultivated in a laboratory dish and molded into the type of cells you want to grow. Singapore doctors are planning on doing just that. Clinical trials will soon be in progress to develop techniques that will take a patient’s fat tissue and create new cartilage, bone, and fat stem cells.
Environment Changes Cause Adult Bone Marrow Stem Cells to Diversify
WebMD Medical News
September 13, 2006
Bone marrow cells appear to have the capacity to replace any cell in the body by being coaxed in a number of diverse ways. In San Francisco, the American Chemical Society hosted three presentations at its annual symposium in early September that will hopefully confirm this hope. The papers that were presented all discussed similar findings.
Intermediate Stem Cells Extracted from Baby Teeth
Greeley Tribune
August 30, 2006
Considered "intermediate", the stem cells of exfoliated deciduous teeth are extracted soon after the tooth becomes loose. Capable to turning into tooth-forming cells (odontoblasts), fat cells, bone cells, and even nerve cells, they are versatile and much less controversial than embryonic stem cells.
Skin Cells Show Potential to Grow Into Organs
The Yomiuri Shimbun
August 11, 2006
Resembling an embryonic stem cell, a new pluripotent cell has been generated using a mouse skin cell by researchers at Kyoto University in Tokyo. The new cell will have the capability to grow into organs and tissues just like embryonic cells.
$1 Million Gift for Stem Cell Research - Largest Private Donation Ever
Rochester Democrat and Chronicle
August 11, 2006
The University of Rochester Medical Center just received the largest private donation ever from a Brighton couple to put toward stem cell research. The couple, Jack (founder of Erdle Corp. in Henrietta) and Norma, did not indicate what variety of stem cell research the donated funds, an sum of $1 million dollars, should be used for.
Thailand Breaks New Ground - Plans Stem-Cell Therapy
The Nation
August 4, 2006
For the first time in the country, Thailand is planning to conduct clinical trials to treat three major neural diseases confirmed the Prasat Neurological Institute. Maiyadhaj described that the procedures involve transplanting developed stem cells into the patients' central nervous system.
World's First, Athens to Host Revolutionary Stem Cell Transplant
ANA
July 26, 2006
A four year old boy will become the recipient of stem cells taken from the umbilical cord of his baby sister who was just born last week in Athens. The boy is suffering from chronic granulomatous disease. Being carried out by geneticist Costas Pangalos and gynecologist Costas Pantos, the procedure will be the world's first for this specific disease.
Human Hair Follicles Source for Multipotent Stem Cells
University of Pennsylvania School of Medicine
July 12, 2006
New sources of adult stem cells appear to have the potential to differentiate into several cell types. Isolated by researchers at the University Of Pennsylvania School Of Medicine, the cells could one day provide the tissue required by individuals for treating a multitude of disorders.
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