Stem Cell Related Patent Number US7078232

Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof

Konkle, Jon; Durham, NC, United States of America
Gimble, Jeffrey M.; Baton Rouge, LA, United States of America

This invention describes a method of differentiating adipose stromal cells to chondrocytes, and uses thereof. Methods and compositions are described which are based on the use of adipose tissue-derived adult stem cells, using a medium comprised of a chondroinductive agent.. Further disclosed are properties of differentiation such that an isolated adipose tissue-derived adult stem cell differentiates to express at least one characteristic of a chondrocyte in combination with a viscous, biocompatible liquid material implanted into a host. Therapeutic applications are described in the clinical treatment and repair of articular cartilage fractures and defects.

Application Number: US2003000713906

Date Filed: 01/14/03

Dated Published: 07/18/06

Assignee: Artecel, Inc.