Stem Cell Related Patent Number US6281408

Efficient method for production of compound transgenic animals

Khillan, Jaspal S.; Cherry Hill, NJ, USA

Described herein are methods for producing a chimeric mouse via the co-culturing of a mixed pool of embryonic stem cells with a mouse morula without a zona pellucida. Applications are included in the research of hormonally influenced gene expression, cell-cell interactions and gene function.

Application Number: US1998000027036

Date Filed: 02/20/98

Dated Published: 08/28/01

Assignee: Thomas Jefferson University, USA