Stem Cell Related Patent Number US6261791

Method for diagnosing cancer using specific PSCA antibodies

Reiter, Robert E.; Los Angeles, CA, USA
Witte, Owen N.; Sherman Oaks, CA, USA

Described herein is the novel prostate stem cell antigen protein, PSCA, and methods of its use in the diagnosis and treatment of prostate cancer, the production of vaccines or the generation of antibodies for use in assays. The invention relates to a novel prostate cell-surface antigen, designated PSCA, which is widely over-expressed across all stages of prostate cancer, bladder cancer and bone metastasis of prostate cancer. Claims of the invention include methods by which antibodies specific to PSCA are used in the diagnosis and treatment of these cancers. This invention represents a continuation of other applications filed by the same assignee and inventors.

Application Number: US1999000318503

Date Filed: 05/25/99

Dated Published: 07/17/01

Assignee: The Regents of the University of California, Oakland, CA, USA