Stem Cell Related Patent Number US5972688

HTm4 methods of treatment and assays, agonists and antagonists

Lim, Bing; Dorchester, MA, USA
Adra, Chaker N.; Boston, MA, USA
Lelias, Jean-Michel; Columbus, OH, USA

This invention described a method of recombinant DNA encoding of the carboxy terminus of the human HTm4 protein. Disclosed are properties of an isolated recombinant DNA molecule comprising extrachromosomal DNA which encodes a mammalian HTm4 protein, a transformed host cell which has been stably transfected with the DNA molecule, and the recombinant HTm4 protein itself. Also disclosed is a method for detecting the presence of a hereditary atopy. Further provided are therapeutic applications in the treatment of cancer and arthritis.

Application Number: US1997000994578

Date Filed: 12/19/97

Dated Published: 10/26/99

Assignee: Beth Israel Deaconess Medical Center, Boston, MA, USA