Stem Cell Related Patent Number US5955357

In-vitro-derived human neutrophil precursor cells

Bender, James G.; Lindenhurst, IL, USA
Maples, Phillip B.; Waukegan, IL, USA
Smith, Stephen L.; Arlington Heights, IL, USA
Unverzagt, Kristen L.; Palatine, IL, USA
Van Epps, Dennis E.; Cary, IL, USA

This invention describes a composition of human neutrophil precursor cells consisting of at least 37% myeloblasts and promyeloblasts, and free of bound monoclonal antibodies. Further disclosed are properties of hematopoietic cell suspensions which contain human neutrophil precursor cells and at least one hematopoietic growth factor. Therapeutic applications are described, such as in the treatment of neutropenia that has been induced by high dose chemotherapy.

Application Number: US1994000295501

Date Filed: 08/23/94

Dated Published: 09/21/99

Assignee: Nexell Therapeutics Inc., Irvine, CA, USA