Stem Cell Related Patent Number US7097832

Intramyocardial injection of autologous bone marrow

Kornowski, Ran; Ramat hasharon, IL, United States of America
Fuchs, Shmuel; Rockville, MD, United States of America
Epstein, Stephen E.; Rockville, MD, United States of America
Leon, Martin B.; New York, NY, United States of America

This invention describes a method of treating cardiac or myocardial conditions which consists of the administration of an effective amount of autologous bone marrow. The bone marrow may optionally be stimulated and/or administered in combination with a pharmaceutical drug, protein, gene or other factor or therapy that may enhance bone marrow production of angiogenic growth factors and/or promote endothelial cell proliferation or migration or blood vessel formation. The advantages offered by this method of enhancing collateral blood vessel formation in a subject